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Lobular carcinoma breast in situ

Lobular carcinoma in situ LCIS means that cells inside some of the breast lobules have started to become abnormal. The lobules are glands that make breast milk. The abnormal cells are all contained within the inner lining of the lobules. Having LCIS means that you have an increased risk of getting invasive breast cancer in either breast in the future.
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Infiltrating Lobular Carcinoma

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Lobular carcinoma in situ - Wikipedia

Lobular carcinoma in situ LCIS is an incidental microscopic finding with characteristic cellular morphology and multifocal tissue patterns. The condition is a laboratory diagnosis and refers to unusual cells in the lobules of the breast. These lesions are preceded by atypical lobular hyperplasia and may follow a linear progression to invasive lobular carcinoma ILC , with specific genetic aberrations. Rarely, terminal ducts may be involved in lobular neoplasia, known as pagetoid spread. Many do not consider LCIS to be a true case of cancer , but it can indicate an increased risk of future cancer.
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MR Imaging Findings of Infiltrating Lobular Carcinoma of the Breast

The stage of cancer indicates the size of the tumor of abnormal cells and whether or not those cells are contained to the place of origin. The most common type of breast cancer is ductal carcinoma in situ DCIS , indicating the cancer cell growth starts in the milk ducts. Stage 0 breast cancer,ductal carcinoma in situ DCIS is a non-invasive cancer where abnormal cells have been found in the lining of the breast milk duct.
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Both significance and treatment remain widely debated, as well as the possible similarities with DCIS. Two hundred patients with pure LCIS were retrospectively analyzed in seven centres from to With a month median follow-up FU , there were no local recurrences LR among 24 patients treated by mastectomy. No specific LR risk factors were identified.

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